Consistent with our findings, previous studies reported that Reg IV expression was induced by CDX2 overexpression in OMC-3 ovarian mucinous carcinoma cells and HT-29 colon cancer cells [42, 45] and suppressed by CDX2 siRNAs in HSC-39 gastric cancer cells [42]. This evidence concerns the gene CDX2 and ovarian mucinous adenocarcinoma.