MYH14 and cardiomyopathy: Although most of the compounds in the present study have been used to treat noncontractile dysfunction in humans (as anticancer, antipsychotic, and antimalarial agents), it is possible that some of them, or derivatives of them, have therapeutic potential for cardiomyopathy where attenuation of contractility is beneficial, as in a hypercontractile state caused by HCM mutations in myosin or actin (6, 47).