Restricting analyses to only brain-expressed, protein-coding genes that were consistently expressed across the 6 AHBA donors (average donor-to-median expression ρ > 0.446, as defined by French and Paus (2015); 4947 genes) included 16 22q11.2 genes and similarly identified significant associations between regional expression of DGCR8 and ΔSA severity in 22q11DS (Supplementary Table 7) and regional expression of P2RX6 with ΔCT severity (Supplementary Table 8). The gene discussed is P2RX6; the disease is 22q11.2 deletion syndrome.