We observed that the impacts of amyloid-PET and tau-PET on diagnosis were overall similar: both PET scans induced significant and similar changes in diagnosis when presented as the first exam (28% due to amyloid-PET and 28% due to tau-PET), while the diagnostic change after the second exam was not significant for both PETs (6% due to amyloid-PET and 9% due to tau-PET). The gene discussed is MAPT; the disease is amyloidosis.