Previously, many studies indicated that the principal reason for OHSS occurrence is that human chorionic gonadotropin (hCG) stimulates ovarian granulosa cells to release a variety of inflammatory factors, such as VEGF, prostaglandin, IL‐6, IL‐8, renin‐angiotensin and prolactin.25 Here, CXCL8 is linked to ovarian hyperstimulation syndrome.