At last, to clarify the role of ATG16L1 in DANCR‐promoted autophagy and Ara‐C resistance in AML cells, we silenced ATG16L1 expression via siRNA transfection in Ara‐C‐treated HL60 cells with or without DANCR overexpression (Fig. 6A). The gene discussed is ATG16L1; the disease is acute myeloid leukemia.