Nonetheless, together with evidence shown in Fig. 6A–C, these results undoubtedly indicate that ATG16L1‐mediated autophagy exerts an antiapoptotic role against the cytotoxicity of Ara‐C, which constitutes a key explanation for the DANCR‐conferred Ara‐C resistance in AML cells. Here, ATG16L1 is linked to acute myeloid leukemia.