CSF3 and type 1 diabetes mellitus: Thus, we have shown that G-CSF, a response factor to infections, mobilizes multipotent progenitors from the bone marrow to the spleen, a process conferring to the progenitors the capacity to enhance the expansion of functional Tregs and thereby, upon adoptive transfer, protecting against type 1 diabetes (T1D) onset in Non Obese Diabetic (NOD) mice6,7 and experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis8.