SYNPO2L and Cognitive impairment: Twenty-seven (16 males) rs56201815-G carriers in ADSP (a total of 29 carriers in which two were excluded from the analyses because they transformed from control to mild cognitive impairment (MCI) during the follow-up in ADSP, and their AD status was unknown) were sampled from 11 cohorts including ACT, ADC, CHAP, MAYO, MIA, MIR, ROSMAP, VAN, ERF, FHS, and RS (Table 2).