PICALM and Alzheimer disease: In addition, we observed well-known AD-associated SNPs among the top hits, including rs12453 in MS4A6A (p = 1.52E−06), rs2296160 in CR1 (p = 6.50E−06), and rs592297 in PICALM (p = 5.26E−05) (Table S2 and Model 1).