Due to the involvement of tau protein in the etiology of AD and PD, the effect of rs12373123 on these diseases might be mediated by MAPT. Indeed, rs12373123 is in high LD with multiple missense SNPs (e.g., rs62056781 and rs74496580) in MAPT, and we found in the snRNA-seq data that rs12373123 is also an eQTL of MAPT in astrocytes. This evidence concerns the gene MAPT and Parkinson disease.