Bioinformatics analysis has shown that circCDR1as plays an important role in the adipogenic/osteogenic differentiation of bone marrow mesenchymal stem cells with steroid-induced osteonecrosis of the femoral head through the CDR1as-miR-7-5p-WNT5B axis; therefore, circCDR1as may serve as a new biomarker for the diagnosis and treatment of steroid-induced osteonecrosis of the femoral head13. The gene discussed is WNT5B; the disease is osteonecrosis.