Furthermore, LONP1 and ClpP mRNA expression were strongly positively correlated in prostate cancer patient samples as well as most other cancer samples (Fig. 1D, E; Fig. S2), whereas human m-AAA protease AFG3L2 had no correlation with LONP1 and ClpP (Fig. S3). The gene discussed is AFG3L2; the disease is Familial prostate cancer.