MYB and cancer: The Ness team found the c-MYB protein bound to over 10,000 promoters in the cancer breast cell line MCF-7, and validated known MYB target genes involved in the cell cycle, such as MYC and CCNB1, or identified new MYB target genes involved in stemness and transcription control such as JUN, KLF4, NANOG and SND119.