SLC5A2 and diabetes mellitus: Moreover, we showed that treatment of DAPA attenuated the rise in the levels of two AMI-associated enzymes (CK-MB and LDH) in response to I/R injury, which was in conformity with a study showing SGLT2 inhibitor exhibited cardioprotective effects and downregulated the serum CK-MB and LDH in DM rats [43].