The mRNA levels of caspase-1 (Fig. 4d), NLRP3 (Fig. 4e), TXNIP (Fig. 4f), ASC (Fig. 4g), and IL-1β (Fig. 4h) in the DCM group were significantly higher than those in the Con group. The gene discussed is TXNIP; the disease is familial dilated cardiomyopathy.