Interestingly, when analyzed the lineal association between the number of LAIR1+ glomerulus/kidney area (mm2) and renal histopathological scores in IL‐35p‐treated lupus mice (Figure 5E), there was an obvious negative association among the number of LAIR1+ glomerulus/kidney area and scores of proteinuria (r = −0.7439, p < 0.05), leukocyturia (r = −0.8589, p < 0.01), hematuria (r = −0.7641, p < 0.05), glomerulonephritis (r = −0.7006, p < 0.05), interstitial nephritis (r = −0.6971, p < 0.05), and vessels infiltration (r = −0.7073, p < 0.05). This evidence concerns the gene LAIR1 and systemic lupus erythematosus.