This was associated with reduced diabetes‐induced glomerular apoptosis, as indicated by reduced Active caspase 3 levels (Figure S3), and with the decrease in glomerular and mesangial expansion in diabetic ∆PodA17 mice compared with diabetic Ct mice, as determined by PAS staining (p < 0.001) (Figure 4A). Here, CASP3 is linked to diabetes mellitus.