MAPK4 and renal cell carcinoma: To screen the putative targets of JMJD6 in RCC, we overlapped the two omics datasets (RNA‐seq, Chip‐seq) to identify 1904 intersecting genes, which were defined as the JMJD6 signature, including well‐known kidney cancer drivers such as vascular endothelial growth factor A (VEGFA), β‐catenin, FGFR1, and MAPK4 (Figure 5G; Table S6).