As a result, genes representative of pivotal drivers of VEGFA signaling, β‐catenin signaling, and cell proliferation in RCC were chosen, including VEGFA/B, SRC proto‐oncogene, nonreceptor tyrosine kinase (SRC), CDC42, CTNNB1, CCND1, MMP9, CDK6, CDKN2D, and HDGF (Figure 5J). This evidence concerns the gene CDC42 and renal cell carcinoma.