Simultaneously, we conducted a multivariate Cox analysis using age, pathological stage, and tumor grade and found that JMJD6 still remained one independent predictive marker for the prognosis of RCC (HR = 1.289, 95% CI, 1.136−1.463, P < 0.001, Figure 2J). The gene discussed is JMJD6; the disease is renal cell carcinoma.