PROM1 and neoplasm: Furthermore, we found that the proportion of CD133+ tumor cells significantly decreased from 68.41 ± 1.83% to 11.63 ± 2.71% (p < 0.001) in Huh7 cells and from 81.20 ± 2.14% to 60.17 ± 3.61% in Hep3B cells (p = 0.007) after the treatment for 7 days (Figure 1D).