As the UCHL1‐eGFP reporter selectively labels small diameter alpha and gamma motor neurons that are not vulnerable to degeneration in ALS,57, 68, 69, 70, 71 we investigated both the NeuN+/ChAT+ LMN subpopulation vulnerable to degeneration and GFP+/ChAT+ LMN subpopulation resistant to degeneration. This evidence concerns the gene UCHL1 and amyotrophic lateral sclerosis.