ERG and cancer: As many AR target genes are also regulated by ERG (Yu et al., 2010; Zhang et al., 2019), the ERG fusion positive cancers may have correlating expression of the androgen-driven fusion transcripts due to overexpression of ERG. For example, correlative analysis with other ETS gene fusions showed that KLK4-KLKP1 expression is associated with ERG but not ETV1, ETV4, or ETV5 (Chakravarthi et al., 2019).