COX5A and Alzheimer disease: The expression levels of Aco2, SDHB-complex II, and Cox5a-complex IV proteins were significantly increased in 1 mg/kg/d DAU-treated 3xTg-AD mice, whereas in 10 mg/kg/d DAU-treated 3xTg-AD mice, the expression level of Ndufs1-complex I was significantly increased, UQCRFS1-complex III and SDHB-complex II showed an upregulated trend (Figures 6E,F).