IFNG and COVID-19: Moreover, higher levels of IFNγ TNFα, IL-2, and IL-10 have been associated with COVID-19 severity, further supporting a pathogenic role (Akbari et al., 2020; Chi et al., 2020; Costela-Ruiz et al., 2020; Del Valle et al., 2020; Lucas et al., 2020; Wang et al., 2020).