HDAC4 and cancer: The antiproliferative and apoptotic effect of EGCG (9) in other types of cancer cells are more described than in cervical cancer. The association of EGCG (9) with the synthetic retinoid compound Am80 leads to apoptosis due to the reduction of HDAC4, 5, and 6, and alteration of the acetylation levels of non-histone proteins, such as p53.