The result also showed that RING1 expression was upregulated in several types of cancers, including CHOL (Bile Duct Cancer), ESCA (Esophageal Cancer), LIHC (Liver Cancer), and PCPG (Pheochromocytoma & Paraganglioma) (Figure 1B) and when compared to their non-cancer counterpart tissues. This evidence concerns the gene RING1 and esophageal cancer.