Furthermore, a large number of studies have shown that ERG is not only an oncogene that is related to a variety of cancers (Wang et al., 2017b; Zhang et al., 2020), it also participates in the embryonic developmental processes, including bone development (Iwamoto et al., 2000), of a variety of organisms (Furlan et al., 2005; Nikolova-Krstevski et al., 2009). Here, ERG is linked to cancer.