The results showed that mice from the maternal diabetic (STZ/P-VEH) group had significantly increased superoxide anion release (see Figure 5D) and 8-oxo-dG formation (see Figure 5E) compared to the control (CTL/P-VEH) group, and amygdala infusion of OXTR (STZ/P-↑OXTR) had no effect, while amygdala infusion of ERβ (STZ/P-↑ERβ) completely reversed the diabetes-mediated effect. Here, ESR2 is linked to diabetes mellitus.