OXTR and diabetes mellitus: Finally, we evaluated the oxidative stress in amygdala tissues from the mice, and the results showed that maternal diabetic (STZ/WT) group displayed significantly increased superoxide anion release (see Figure 3D) and 8-oxo-dG formation (see Figures 3E,F) compared to control (CTL/WT) group; there was no effect in OXTR knockout (OXTR–/–) mice compared to the control (CTL/OXTR–/–) group, but the OXTR knockout further potentiated maternal diabetes (STZ/OXTR–/–) -mediated oxidative stress compared to STZ/WT group.