The myCAF marker genes (ACTA2 and TPM1) and common CAF marker genes (COL1A1 and fibroblast activation protein alpha, FAP) were highly expressed in clusters 1 and 2, whereas expression of iCAF- or apCAF-related marker genes was not observed in the original AD-MSCs (Fig. 4b,c, and Fig. S4a,b). The gene discussed is COL1A1; the disease is Alzheimer disease.