UTX mutations have also been found in various types of human cancers: clear cell renal cell carcinoma, medulloblastoma, chronic myelomonocytic leukemia, acute lymphoblastic leukemia, transitional cell carcinoma of the bladder, and high-grade muscle-invasive urothelial bladder carcinoma and others12,13. The gene discussed is KDM6A; the disease is clear cell renal carcinoma.