UTX mutations have also been found in various types of human cancers: clear cell renal cell carcinoma, medulloblastoma, chronic myelomonocytic leukemia, acute lymphoblastic leukemia, transitional cell carcinoma of the bladder, and high-grade muscle-invasive urothelial bladder carcinoma and others12,13. Here, KDM6A is linked to acute lymphoblastic leukemia.