RUNX1 and leukemia: Kataegis occurred particularly frequently at a per-sample level between chr20:31050000-31080000 (Additional file 1: Figure S1) which corresponds to the region of NOL4L/C20orf112 (chr20:31,030,862-31,071,385) a known fusion partner of RUNX1 and PAX5 in leukaemia [47].