PELI1 and Sepsis: Consequently, we found that the inhibition of BAL neutrophil, BAL protein concentrations, lung bacterial CFU, BAL fluid hemoglobin (Hgb) concentration, lung injury, BAL fluid OD540 and lung tissue homogenates at OD620, and circulating platelet counts were increased in lung injury in Pellino1−/− mice of sepsis (Fig. 2a and h).