whereas the tumor volume in ABCC5-overexpressing MTA-treated mice increased by 2.7-fold (untreated AdvCtrl mice: 665 mm3, MTA-treated AdvCtrl mice: 195 mm3, untreated AdvABCC5 mice: 703 mm3, MTA-treated AdvABCC5 mice: 412 mm3; AdvCtrl-MTA group vs. untreated AdvCtrl mice group: p < 0.01, AdvABCC5-MTA group vs. untreated AdvABCC5 mice group: p < 0.01). The gene discussed is ABCC5; the disease is neoplasm.