Specifically, we found that expression of SLC7A7 was significantly correlated with chemokine (C–C motif) ligand (CCL)-2, CD68, IL10 of TAMs, IRF5 of M1 phenotype, CD163, VSIG4 and MS4A4A of M2 phenotype in NSCLC (P < 0.0001; Fig. 6a, b). The gene discussed is IRF5; the disease is non-small cell lung carcinoma.