Compared with the wild-type genotypes of CYP1A1 rs1048943 (TT) or SULT1A1 rs1042028 (CC), the heterozygous variant genotypes of CYP1A1 rs1048943 (TC) or SULT1A1 rs1042028 (CT) showed significantly higher risk in breast cancer, with ORs of 2.37 (95% confidence interval [CI] = 1.27–4.43) and 2.21 (95% CI = 1.20–4.05), respectively. The gene discussed is CYP1A1; the disease is breast carcinoma.