Similar to DFO responses in HIB1B and C3H/10T1/2 cells (Fig. 5), DFO treatment resulted in depletion of iron-storage protein FTL, stabilization of IRP2, and a robust increase of TfR1 expression in adipocytes as a collective sign of iron deficiency (Fig. 7C). This evidence concerns the gene IREB2 and Iron deficiency anemia.