The study of Molnar et. al. 2009 analyzed the impact of 13 ALS-SOD1 mutations (A4V, L38V, G41S, H46R, G72Y, D76S, G85R, D90A, G93A, D124V, D125H, and S134N) on protein structure and dynamics using hydrogen/deuterium exchange mass spectrometry [95]. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.