The genes were also correlated with amyloid-beta and tau phosphorylation related processes, including positive regulation of amyloid fibril formation (fold enrichment > 100, qc = 0.0181), regulation of amyloid-beta formation (fold enrichment = 26.78, qc = 0.022), positive regulation of tau-protein kinase activity (fold enrichment > 100, qc = 0.00178), and regulation of protein dephosphorylation (fold enrichment = 9.99, qc = 0.0174), which are well-known neuropathology of AD. Here, MAPT is linked to Alzheimer disease.