Table.1 demonstrates the animal studies of RIC and cytokine release, performed within the last 5 years, following myocardial infarction and reperfusion [9, 15, 33, 114, 136, 141, 152] Across several studies, RIC was associated with reduced levels of the pro-inflammatory cytokines, IL-1β, TNF-α and HMGB1 following reperfusion [114, 152]. The gene discussed is IL1B; the disease is myocardial infarction.