NOS2 and lymphoma: As shown in Figures 9(a) and 9(b), LIUS upregulated two (thioredoxin reductase 1 (Txnrd1) and glutathione peroxidase 3 (Gpx3)) and downregulated two oxidative/antioxidative genes (apolipoprotein E (Apoe) and inducible NO synthase (Nos2)) in BM cells, respectively, and LIUS upregulated two oxidative/antioxidative genes such as Gpx3 and Nos2 in lymphoma cells, suggesting that LIUS modulated the ROS regulatome.