Here, we also found that the cutoff of ≥10%, which is commonly used in IDH-wildtype GBM PSQ testing, was not suitable for IDH-mutant GBM, probably as a consequence of the differing molecular features, such as chromosome 10 loss, between IDH-mutant and IDH-wildtype GBM2,29. The gene discussed is IDH2; the disease is glioblastoma.