In the primary IDH-mutant GBM cases, the median PFS in months was 14.90 (unmethylated, <30%) and 82.90 (methylated, ≥30%), and the median OS in months was 19.50 (unmethylated, <30%) and 127.10 (methylated, ≥30%). The gene discussed is IDH2; the disease is glioblastoma.