In the last decades, many genetic variants tied up with Parkinson's disease have been identified, such as alpha-synuclein (SNCA), leucine-rich repeat kinase 2 (LRRK2), p10-induced putative kinase 1 (PINK1), DJ-1, parkin (PARK2), and ATPase type 13A2 (ATP13A2), leading to a better understanding of the complexity of its genetic patterns. The gene discussed is PINK1; the disease is Parkinson disease.