PTEN and neoplasm: There are various proteins like Bcl-2-interacting Beclin1 (BECN1/ATG6), Atg4c [117], Bax-interacting factor-1 (Bif-1) [118], BH3-only proteins [7], DAP kinase [119], ultraviolet radiation resistance-associated gene (UVRAG) [120], and PTEN [121] involved in autophagy that shows its role in tumor suppression (Figure 6).