IKBKE and cardiac hypertrophy: The echocardiographic analysis of cardiac function showed a significant decrease in the EF, FS, and E/A, as well as an increase in the left ventricular posterior wall diastole (LVPWd) in WT mice after 8 weeks of Ang II infusion, which indicated the attenuation of myocardial hypertrophy and deterioration of LV function in IKKε-KO mice compared with those of WT mice (Figures 2(c) and 2(d)).