TGFB1 and neuroblastoma: Here, we established an oxygen-glucose deprivation/reoxygenation (OGD/R) model in human neuroblastoma cell SH-SY5Y to simulate IRI, identify a TGF-β inhibitor of punicalin alleviating OGD/R-induced neuroblastoma injury from PGL extraction, and elucidate the mechanism of punicalin-suppressing cell injury via TGF-β-mediated oxidative stress and cell cycle arrest.