Among the BC-associated targets of FDY003, TP53, SRC, PIK3R1, VEGFA, AKT1, EGFR, CYP1A1, CYP3A4, JUN, CDK1, and ESR1 were hub nodes (Figure 4), suggesting that the nodes act as important targets mediating the therapeutic effects of FDY003 against BC cells. The gene discussed is ESR1; the disease is breast cancer.