In contrast, co-culturing cytokine treated ADSC with primary DLBCL cells clearly impacted the expression of podoplanin, VCAM-1, and ICAM-1 on the recovered ADSC, with addition of MDM further modulating this effect (Figure 5B, Supplementary Figure 4A), suggesting that MDM may foster unique interactions between these cells, stroma and primary DLBCL cells. The gene discussed is PDPN; the disease is diffuse large B-cell lymphoma.