Previous studies have confirmed that CCNB1 is highly expressed in multiple cancers, including cervical cancer, gastric cancer, head, and neck squamous cell carcinoma, non-small-cell lung cancer, prostate cancer, oral cancer, and esophageal cancer (Zhang et al., 2018; Farshadi et al., 2019; Żuryń et al., 2019). Here, CCNB1 is linked to Familial prostate cancer.