Cordycepin restrains the proliferation of cancer cells by triggering adenosine A3 receptors followed by the Wnt signaling pathway, including glycogen synthase kinase three beta (GSK3β) activation and cyclin D1 inhibition (Yoshikawa et al., 2004, 2007; Yoshikawa et al., 2008). The gene discussed is CCND1; the disease is cancer.