ANXA5 and breast cancer: As shown in Figure 2A, both early apoptosis (Annexin V positive, PI negative) and late apoptosis (Annexin V positive, PI positive) of the breast cancer cells were significantly increased in a concentration-dependent manner with the rates increasing from 5.9% (Control) to 44.0% (TAIII 10 μM) and 67.5% (TAIII 15 μM), respectively.