TNF and inflammatory bowel disease: Other IBD therapies include (i) corticosteroids, immunomodulatory drugs such as Purinethol (Mercaptopurine), Azasan (azathioprine), and Trexall (methotrexate), and (ii) tumor necrosis factor-alpha (TNFα) inhibitors such as Remicade (infliximab) and Humira (adalimumab) (Flynn and Eisenstein, 2019[11]).