Hs-cTnI has been considered as a specific and sensitive diagnostic marker for myocardial infarction, as evidence suggested that by using a hs-cTnI assay, patients with an acute myocardial infarction can be identified reliably with 100% sensitivity and 100% negative predictive value within three hours of admission 11. This evidence concerns the gene TNNI3 and myocardial infarction.