When EC cases were classified by degree of tumor differentiation, no statistically-significant difference in circulating ENO1 levels was found between grade 2 (n=11), grade 2/3 (n=7), and grade 3 tumors (n=14) (mean±SE pg/ml, 2143±178, 2161±384, 2225±326, respectively; p=0. Here, ENO1 is linked to neoplasm.