ENO1 and Barrett esophagus: A trend toward increased ENO1 levels was found in the sequence EAC patients, BE patients, healthy subjects [median (range) pg/ml: 1867 (538-4636), 2273 (1461-4737), 3494 (1629-6596), respectively, p<0.0001, Kruskal-Wallis One Way Analysis of Variance on Ranks; EAC vs. BE, p=0.0758; EAC vs. normal donors, p<0.0001; BE vs. normal donors, p=0.0647 (Dunn's multiple comparisons test)] (Figure 5C).