When EC cases were classified by degree of tumor differentiation, no statistically significant difference in ENO1 expression was found between grade 2 (n=14) (IRS mean±SE: 5.93±0.77), grade 2/3 (n=10) (IRS mean±SE: 3.84±1.21), and grade 3 tumors (n=16) (IRS mean±SE: 3.46±0.87) (One Way Analysis of Variance p=0.4671) (data not shown). Here, ENO1 is linked to neoplasm.